CG-PLM-4

Agilent Technologies

in situ oligonucleotide

Homo sapiens

Agilent's Human Genome CGH Microarray Kit 44B is a high-resolution, high performance 60-mer oligonucleotide-based microarray that contains approximately 43,000 probes sourced from the NCBI genome Build 35. This microarray, in addition to containing all the Build 35-mapped biological probes from the previously-released CGH 44A microarray (Build 34), contains an additional ~2,500 probes to expand the coverage in the human genome.

Features

Comprehensive genome-wide coverage - Consists of~43,000 60-mer oligonucleotide probes that span both coding and noncoding sequences with an average spatial resolution of ~35kB.

Optimized probe design for CGH applications - Maximize confidence in microarray performance through the use of Agilent's powerful probe design algorithms and validation processes. Probe performance was validated in multiple model systems with defined aberrations.

High resolution and sensitivity - Reproducibly detect genome lesions including single-copy and homozygous deletions, as well as variable amplicons - enabled by Agilent's in situ synthesized 60-mer oligonucleotide probes.

Nanogram sample input - Only 100ng of total genomic DNA per sample is required so that you can conserve precious, limited, and hard-to-procure clinical samples.

Total genomic DNA with NO complexity reduction -Eliminates potential biases introduced by the process and maximizes the biological utility of the sample with a single, simplified sample preparation.

Focused coverage - Probe selection bias toward genes, particularly cancer-related ones, ensures adequate coverage in the most commonly studied genomic regions. Well-characterized genes are each represented by at least one 60-mer oligonucleotide probe and cancer-relevant genes are each represented by at least two or more probes.

44K slide format printed using Agilent's SurePrint technology

GPL2879 is the Feature Number version in GEO.

2005-08-18 12:00:41 by Ilari Scheinin

2012-02-09 15:27:21 by Ilari Scheinin